![]() The dorsal organizer plays a major role in the process of axis formation (). So, the correct answer is 'Dorsal lip of the blastopore'. Roles of the Dorsal Organizer in the Formation of Dorso-ventral and Anterior-posterior Axes. Hans Spemann and Hilde Mangold experiments proved that the dorsal lip of blastopore makes the neural tubes, cartilaginous skeletons, mesoderm etc and therefore called as the Specman's primary organizer. ![]() In embryology, an organizer is the morphogenetic effect caused by one organic tissue which produces a chemical molecule that affects another part of the embryo to form a part which otherwise would not have produced. The research by Hans Spemann (German embryologist) and his colleague Hilde Mangold did a transplantation experiment in frogs which led to the discovery of organizers. In the development of a frog embryo, the dorsal lip of the blastopore would be the spearman’s primary organizer. The newly formed zygote later goes through the mitotic divisions and forms a multicellular embryo. This is a dramatic example of embryonic induction.The dorsal lip of the blastopore is call the ORGANIZER. The Primary Organizer has a dorsalizing effect, and together with the Sperm Entry Point (SEP) gives rise to the dorsal/ventral axis. The dorsal lip of the blastopore is the only self differentiating region in the early gastrula because when transplanted it can initiate gastrulation and affect the surrounding host tissue. It gives rise to the Primary Organizer, which is the dorsal lip of the blastopore (DLB). The embryogenesis starts with the fusion of the egg cell and sperm cell and gets fertilized, from which a zygote (diploid) is developed. The Nieuwkoop Center is the dorsal- and vegetal-most cell of the early blastula. Hint: The process of formation and development of an embryo is known as embryogenesis.
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